Spectrophotometric Determination Of Valsartan In Pure Form And In Its Pharmaceutical Preparations

An easy, rapid and economical spectrophotometric method for  determination of  Valsartan (Val), by reaction with 4-chloro-7-nitrobenzofurazan (NBD-Cl) as reagent in an alkaline interemediate. This is based on the forming of product between (Val) chromogenic (NBD-Cl), to produce a brown color at (pH 11.9) λmax. 470 nm.  Beer’s Law obeyed concentrations range (0.4-14.8 µg/ml), molar absorptivity (1.05×104 L/mol.cm) correlation coefficient 0.9827, The limit detection was 0.557 µg/ml. suggested prosperity implement in  pure form its pharmaceutical formulations (tablets).